#Multivalent protein scaffold pdf#

108050009401 Fibronectin type III Proteins 0.000 claims description 9.102000002090 Fibronectin type III Human genes 0.000 claims description 9.108091006822 Human Serum Albumin Proteins 0.000 claims description 11.102000008100 Human Serum Albumin Human genes 0.000 claims description 11.230000000875 corresponding Effects 0.000 claims description 25.230000000275 pharmacokinetic Effects 0.000 claims description 63.150000001413 amino acids Chemical group 0.000 claims description 104.239000002202 Polyethylene glycol Substances 0.000 claims description 104.229920001223 polyethylene glycol Polymers 0.000 claims description 128.229920001184 polypeptide Polymers 0.000 claims abstract description 319.102000016359 Fibronectins Human genes 0.000 title abstract 2.108090000623 proteins and genes Proteins 0.000 title abstract description 184.102000004169 proteins and genes Human genes 0.000 title abstract description 184.230000037320 fibronectin Effects 0.000 title claims abstract description 55.108010067306 Fibronectins Proteins 0.000 title claims abstract description 55.NICHOLAS Publication of US20090299040A1 publication Critical patent/US20090299040A1/en Application granted granted Critical Publication of US8221765B2 publication Critical patent/US8221765B2/en Status Active legal-status Critical Current Adjusted expiration legal-status Critical Links Assignors: CARBONI, JOAN, GOTTARDIS, MARCO M., ATTAR, RICARDO M., CAMPHAUSEN, RAY, CARVAJAL, IRVITH M., FURFINE, ERIC, MARSH, H. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority to US12865108P priority Critical Priority to US21298209P priority Priority to US17839509P priority Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co Priority to US12/470,989 priority patent/US8221765B2/en Assigned to BRISTOL-MYERS SQUIBB COMPANY reassignment BRISTOL-MYERS SQUIBB COMPANY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Original Assignee Bristol Myers Squibb Co Priority date (The priority date is an assumption and is not a legal conclusion.

Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) Nicholas Marsh Marco Gottardis Joan Carboni Ricardo Attar Current Assignee (The listed assignees may be inaccurate. ( en Inventor Ray Camphausen Eric Furfine Irvith M. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Active, expires Application number US12/470,989 Other versions US20090299040A1

#Multivalent protein scaffold pdf#

Google Patents Multivalent fibronectin based scaffold domain proteinsДownload PDF Info Publication number US8221765B2 US8221765B2 US12/470,989 US47098909A US8221765B2 US 8221765 B2 US8221765 B2 US 8221765B2 US 47098909 A US47098909 A US 47098909A US 8221765 B2 US8221765 B2 US 8221765B2 Authority US United States Prior art keywords seq polypeptide loop domain amino acid Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents US8221765B2 - Multivalent fibronectin based scaffold domain proteins US8221765B2 - Multivalent fibronectin based scaffold domain proteins